Father's work

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AARON KLUG

1 - Father's work

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Title: Father's work

Listeners: John Finch Ken Holmes

John Finch is a retired member of staff of the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. He began research as a PhD student of Rosalind Franklin's at Birkbeck College, London in 1955 studying the structure of small viruses by x-ray diffraction. He came to Cambridge as part of Aaron Klug's team in 1962 and has continued with the structural study of viruses and other nucleoproteins such as chromatin, using both x-rays and electron microscopy.

Kenneth Holmes was born in London in 1934 and attended schools in Chiswick. He obtained his BA at St Johns College, Cambridge. He obtained his PhD at Birkbeck College, London working on the structure of tobacco mosaic virus with Rosalind Franklin and Aaron Klug. After a post-doc at Childrens' Hospital, Boston, where he started to work on muscle structure, he joined to the newly opened Laboratory of Molecular Biology in Cambridge where he stayed for six years. He worked with Aaron Klug on virus structure and with Hugh Huxley on muscle. He then moved to Heidelberg to open the Department of Biophysics at the Max Planck Institute for Medical Research where he remained as director until his retirement. During this time he completed the structure of tobacco mosaic virus and solved the structures of a number of protein molecules including the structure of the muscle protein actin and the actin filament. Recently he has worked on the molecular mechanism of muscle contraction. He also initiated the use of synchrotron radiation as a source for X-ray diffraction and founded the EMBL outstation at DESY Hamburg. He was elected to the Royal Society in 1981 and is a member of a number of scientific academies.

Tags: Lithuania, Baltic States, South Africa, Durban, Boer War

Duration: 1 minute, 55 seconds

Date story recorded: July 2005

Date story went live: 24 January 2008

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12 1. Father's work

Duration: 1 minute, 55 seconds.

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2. School

Duration: 6 minutes, 4 seconds.

287 0

3. Reading and the book that got me into science

Duration: 3 minutes, 18 seconds.

274 0

4. Life in South Africa and studying at the University of Witwatersrand

Duration: 6 minutes, 13 seconds.

164 0

5. An MSc and PhD at Cape Town University

Duration: 8 minutes, 7 seconds.

132 0

6. RW James

Duration: 1 minute, 1 second.

112 0

7. Meeting my wife and moving to Cambridge

Duration: 2 minutes, 3 seconds.

174 0

8. Finding work at Cambridge

Duration: 4 minutes, 38 seconds.

136 0

9. My work on steel helped with accelerating the growth of TMV

Duration: 3 minutes, 15 seconds.

87 0

10. Politics and working on haemoglobin

Duration: 3 minutes, 57 seconds.

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12 Lewis Wolpert
Biologist

Becoming a soil mechanic

Keywords: South Africa

Tomas Venclova
Poet

'Stay in Lithuania'

Keywords: Lithuania

Norman Routledge
Teacher

Father's lack of communication

Keywords: fathers

Freeman Dyson
Physicist

Father's move to London

Keywords: Fathers

Brian Sewell
Art critic

My father's suicide

Keywords: fathers

Hans Bethe
Physicist

My father's scientific influence on me

Keywords: fathers

vaneyck says:
Aaron Klug is a scientist of great ability who tells his stories extremely well, though he assumes... Read more

Aaron Klug is a scientist of great ability who tells his stories extremely well, though he assumes knowledge on the part of his listeners that most of us,(I included), do not have. But this is not a flaw, in my eyes - I feel I have been given a whole new range of information to look into. I came to Web of Stories looking for the interviews with Sydney Brenner, just having re-read H.F. Judson's The Eighth Day of Creation. After listening to Brenner - I was not disappointed -I went to the Klug interviews, as he is also mentioned favorably in the book. I was even better pleased with Klug's stories, and am starting to listen to them a second time through. I highly recommend them to anyone who has even a passing interest in the progress of biological knowledge in the second half of the 20th century. You will meet a brilliant man who has had a very interesting career and who describes it very well.

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Becoming a soil mechanic

'Stay in Lithuania'

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