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NEXT STORY

How I met my husband, Thomas Hodgkin

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Thomas Hodgkin's family history
Dorothy Hodgkin Scientist
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My husband was Thomas Hodgkin who belongs to the same family as Alan Hodgkin. They are both grandsons of Thomas Hodgkin, the Quaker historian who wrote on Italy and her invaders. Thomas’s father was Robin Hodgkin who went to Oxford University and became a historian of the Anglo-Saxons so he wrote a long book on the history of the early Anglo-Saxons. Alan’s father was George Hodgkin who, after the First World War, wanted to go and do relief work in the East and he unfortunately died of... of typhoid I think in Beirut, in Baghdad, at the end of the First World War, leaving his mother with three little children to bring up.

 

British pioneer of X-ray crystallography, Dorothy Hodgkin (1910-1994), is best known for her ground-breaking discovery of the structures of penicillin, insulin and vitamin B12. At age 18, she started studying chemistry at Somerville College, Oxford, then one of the University of Oxford colleges for women only. She also studied at the University of Cambridge under John Desmond Bernal, where she became aware of the potential of X-ray crystallography to determine the structure of proteins. Together with Sydney Brenner, Jack Dunitz, Leslie Orgel, and Beryl Oughton, she was one of the first people in April 1953 to see the model of the structure of DNA, constructed by Francis Crick and James Watson. She was awarded the 1964 Nobel Prize in Chemistry and is also known for her peace work with organisations such as Science for Peace and the Medical Aid Committee for Vietnam. All recorded material copyright of The Biochemical Society.

Listeners: Guy Dodson

Guy Dodson studied chemistry and physical science at the University of New Zealand, followed by a PhD on the crystallographic study of an alkaloid. In 1961, he came to Oxford to work on the crystal structure of insulin. In the mid 1970s Guy and his wife moved to York University to establish a laboratory. In addition to insulin studies the laboratory has investigated many complex molecules of medical significance, including haemoglobin, myoglobin, HIV related proteins, proteases and proteins involved in managing nucleic acids in cells. In 1993, he went to the NIMR in London to establish a crystallographic group in an environment that spanned molecular, physiological and disease-related disciplines. Here his research began on some cell signalling proteins. His interests on medically relevant proteins included prions, malarial and TB proteins, and some clinically relevant thrombin inhibitors. Guy Dodson retired in 2004 but is still finding much to do in York and the NIMR.

Tags: World War I, Thomas Hodgkin, Alan Hodgkin

Duration: 1 minute, 16 seconds

Date story recorded: 1990

Date story went live: 02 June 2008