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Personal motivation


Looking for new cells
Avrion Mitchison Scientist
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If I wanted to look for new cells now, and there are plenty of people who are looking for new cells, I would look at it in a much more specialised way, I would look for it in some of the epithelia and particularly in association with epithelia, where there's already hints of something interesting going on. For example, the nasal epithelium which in animals, if you contact it, it seems to be a brilliant way of generating suppression- and just how that operates is completely. But I think we would love- like to know more about that- that epithelium, but we would also like to know about the lungs, we'd like to know about the gut, inflammatory bowel disease. I think there's a lot more there- to come there. And in the course of that I think we'll find, we will find unique populations of cells. How unique they will be nobody knows, because after all we don't really know whether these famous T-regs which people are talking about just now, really how distinct they are from cells which are cytokine polarised to make IL-10. There's- there's a lot of confusion about them.

Avrion Mitchison, the British zoologist, is currently Professor Emeritus at University College London and is best known for his work demonstrating the role of lymphocytes in tumour rejection and for the separate and cooperative roles of T- and B-lymphocytes in this and other processes.

Listeners: Martin Raff

Martin Raff is a Canadian-born neurologist and research biologist who has made important contributions to immunology and cell development. He has a special interest in apoptosis, the phenomenon of cell death.



Listen to Martin Raff at Web of Stories



Duration: 1 minute, 13 seconds

Date story recorded: June 2004

Date story went live: 29 September 2010