a story lives forever
Sign in
Form submission failed!

Stay signed in

Recover your password?
Form submission failed!

Web of Stories Ltd would like to keep you informed about our products and services.

Please tick here if you would like us to keep you informed about our products and services.

I have read and accepted the Terms & Conditions.

Please note: Your email and any private information provided at registration will not be passed on to other individuals or organisations without your specific approval.

Video URL

You must be registered to use this feature. Sign in or register.


Getting papers published - then and now


Experimenting with irradiating mice
Avrion Mitchison Scientist
Comments (0) Please sign in or register to add comments
I did one mouse experiment which was- I- had something to do with the future. It was good. Which was to show that if you irradiated mice, you got a better transferred response. What was the response? I've actually forgotten, but some immune response. They- the irradiation helped a lot. And that led me to go and spend a couple of months in- in Harwell, in the Atomic Energy Research establishment where there was a Medical Research Council unit led by John Lightet and I did work in parallel with work which was done there by Ford who showed- they showed that in an irradiated animal you could re-colonise the spleen as judged by chromosome markers. And I showed that if you irradiated an animal you could re-colonise the spleen as judged by transplantation antigens. It was an all transplantation antigen tests, which was almost all anyone knew about apart from these chromium plated red cells, and they both get the same result This was with bone marrow? This was with bone marrow, or spleen, there was enough hematopoietic cells in spleen to do it.

Avrion Mitchison, the British zoologist, is currently Professor Emeritus at University College London and is best known for his work demonstrating the role of lymphocytes in tumour rejection and for the separate and cooperative roles of T- and B-lymphocytes in this and other processes.

Listeners: Martin Raff

Martin Raff is a Canadian-born neurologist and research biologist who has made important contributions to immunology and cell development. He has a special interest in apoptosis, the phenomenon of cell death.



Listen to Martin Raff at Web of Stories



Duration: 1 minute, 28 seconds

Date story recorded: June 2004

Date story went live: 24 January 2008