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The four groups investigating T-cells


The next step in understanding tolerance
Avrion Mitchison Scientist
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The next step forward in our understanding of tolerance, very much involves TB collaboration and the role of thymus derive cells on the one hand, and bone marrow's derive cells on the other, T-cells and B-cells. And, I'd just like to back over what we had touched on so far, which is that there is no doubt that the end of the 1960s, and in particular 1969, was the decisive- you know, when TB co-operation was discovered and worked out, mostly worked out, that the elements which were needed for that were the discovery that T-cells, a separate population of cells, comes out of the thymus called T-cells, and that's the work of Jacques Miller and to an extent which I'm not quite clear about, contemporary work done by Bob Goode and his colleagues in America. One mainly on mice and the other mainly on humans, but some overlap.

Avrion Mitchison, the British zoologist, is currently Professor Emeritus at University College London and is best known for his work demonstrating the role of lymphocytes in tumour rejection and for the separate and cooperative roles of T- and B-lymphocytes in this and other processes.

Listeners: Martin Raff

Martin Raff is a Canadian-born neurologist and research biologist who has made important contributions to immunology and cell development. He has a special interest in apoptosis, the phenomenon of cell death.



Listen to Martin Raff at Web of Stories



Duration: 1 minute, 22 seconds

Date story recorded: June 2004

Date story went live: 24 January 2008