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The discovery of ErbB4

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Joys of being at Harvard University
Gerald Fischbach Scientist
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But I wanted to say something more about my first years at Harvard. One of the people I grew close to was in the neurobiology department, Paul Patterson, who passed away a few years ago of lung cancer. He was working on sympathetic ganglia and did a lot of work with Story Landis, a wonderful scientist, who succeeded me as director of NINDS. But the three of us were good friends and that was part of the joy of being at Harvard.

But we left it to go to Washington University in St. Louis, where we continued the purification of what I then called ARIA, the Acetylcholine Receptor Inducing Activity. Once we got closer, a young student, Ted Usdin, finished the purification beautifully and we began to obtain sequence information, what is this protein. And that study, the purification, which took a long time, and the sequencing, began in St. Louis and ended up at Harvard number two, the second time I was at Harvard.

Gerald Fischbach (b. 1938) is an American neuroscientist and pioneering researcher. He pioneered the use of nerve cell cultures to study the electrophysiology, morphology and biochemistry of developing nerve-muscle and inter-neuronal synapses.

Listeners: Christopher Sykes

Christopher Sykes is an independent documentary producer who has made a number of films about science and scientists for BBC TV, Channel Four, and PBS.

Tags: Paul Patterson, Ted Usdin

Duration: 1 minute, 44 seconds

Date story recorded: July 2023

Date story went live: 16 May 2025