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Dual recognition appeared as a bolt out of the blue


Collaboration and friendship with Fritz Bach
Jan Klein Scientist
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Perhaps it is of some interest that although we parted in the interpretation of the data, many of the data were generated together with Fritz Bach.  And Fritz Bach was an expert... was one of the persons who discovered the MLC reaction, the mixed lymphocyte reaction. And so he was very interested in applying it to the H2 complex and he approached me and we collaborated on many of the projects and then we published several papers together and we remained during that entire period friends.  And so it was a controversy, purely scientific, as I think there should be and that didn't affect the relationship between the people. Later I lost track of Fritz because he went into different areas, but at that period of time, he was then at Wisconsin, it was a busy interaction between the two groups. I was still in Ann Arbor, Michigan and he was, as I said, in Wisconsin so we frequently visited each other and of course we were shipping mice to him all the time. It was a good collaboration actually.

Born in 1936, Jan Klein is a Czech-American immunologist who co-founded the modern science of immunogenetics – key to understanding illness and disease. He is the author or co-author of over 560 scientific publications and of seven books including 'Where Do We Come From?' which examines the molecular evolution of humans. He graduated from the Charles University at Prague in 1955, and received his MS in Botany from the same school in 1958. From 1977 to his retirement in 2004, he was the Director of the Max Planck Institute for Biology at Tübingen, Germany.

Listeners: Colm O'hUigin

Colm O'hUigin is a senior staff scientist at the US National Cancer Institute. He received his BA, MSc and PhD at the Genetics Department of Trinity College, Dublin where he later returned as a lecturer. He has held appointments at the Center for Population and Demographic Genetics, UT Houston, and at the University of Cambridge. As an EMBO fellow, he moved in 1990 to the Max Planck Institute for Biology in Tübingen, Germany to work with Jan Klein and lead a research group studying the evolutionary origins of immune molecules, of teeth, trypanosomes and of species.

Tags: MLC reaction, mixed lymphocyte reaction, Fritz Heinz Bach

Duration: 2 minutes, 59 seconds

Date story recorded: August 2005

Date story went live: 24 January 2008