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Acceptance of the paper


Still working on mutagenesis
Sydney Brenner Scientist
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Now at the same time, we were working still on mutagenesis, so you have to imagine that one went from one thing to the other. We were doing... we were doing the whole project, it all had a whole... though today you would say, 'Well, what are you doing density gradient with the one hand and genetics with the other? But it had this… it had this whole, because what we were interested in was what is the connection between what's written in the DNA and what's written in the protein. That's all we wanted to know and we would use any… we would use anything... any method to try to get to that root. Now the mutagenesis thing which was going on simultaneously is quite… is interesting in the sense that at one point Francis decided that he would start to do genetics.

South African Sydney Brenner (1927-2019) was awarded the Nobel Prize in Physiology or Medicine in 2002. His joint discovery of messenger RNA, and, in more recent years, his development of gene cloning, sequencing and manipulation techniques along with his work for the Human Genome Project have led to his standing as a pioneer in the field of genetics and molecular biology.

Listeners: Lewis Wolpert

Lewis Wolpert is Professor of Biology as Applied to Medicine in the Department of Anatomy and Developmental Biology of University College, London. His research interests are in the mechanisms involved in the development of the embryo. He was originally trained as a civil engineer in South Africa but changed to research in cell biology at King's College, London in 1955. He was made a Fellow of the Royal Society in 1980 and awarded the CBE in 1990. He was made a Fellow of the Royal Society of Literature in 1999. He has presented science on both radio and TV and for five years was Chairman of the Committee for the Public Understanding of Science.



Listen to Lewis Wolpert at Web of Stories



Tags: Francis Crick

Duration: 1 minute, 2 seconds

Date story recorded: April-May 1994

Date story went live: 24 January 2008